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The images below show screen capture of a 2D line plot with and without anti-aliasing (click to pop up larger image):
Turn Anti-Aliasing On
You can toggle Anti-Aliasing on and off using the button on Graphs toolbar for the active graph.
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For the graphs that has Anti-Aliasing turned on, there are additional global settings to fine tune which type of drawing to use anti-aliasing. These can be found on Graph tab of Tools: Options dialog.